Three major trends in the development of antihypertensive drugs
Poor compliance is one of the main problems to be solved in antihypertensive treatment.After decades of development, antihypertensive drugs have developed from early thiazide diuretics, beta-blockers, calcium antagonists and angiotensin-converting enzyme inhibitors (Puls) to vascular tension Receptor blockers (sartans).
Based on the current status and clinical needs of antihypertensive treatment, the current research and development of antihypertensive drugs mainly develops in three major directions: new target, slow release technology and fixed compound preparation.
In the past 15 years, there are many fixed-dose combination drugs consisting of two or more drugs in the world.